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Figure 7 | Journal of Neuroinflammation

Figure 7

From: TGFβ signaling in the brain increases with aging and signals to astrocytes and innate immune cells in the weeks after stroke

Figure 7

TGFβ signaling in reactive astrocytes increases in the stroke penumbra after stroke. A.) Representative image (40×) showing GFAP (astrocytes) colocalized with pSmad2 after stroke. Image is from a young female mouse at day 14 post stroke. See additional file 4 for a 3D projection B.) GFAP immunoreactivity increases in the first 7 days after stroke with the majority of astrocytes colocalizing with pSmad2 (*p < 0.05 compared to sham).

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