Table 2 Microarray studies of microglia transduced with Ad-IRF3 or Ad-GFP and stimulated with IL-1/IFNγ:
Gene | Ratio (IRF3/GFP) | Difference in expression (IRF3 minus GFP) |
|---|---|---|
IFNB (IFNβ) | 3.5 | 418 |
IRF7 | 2.3 | 1441 |
IFIT1 | 11.2 | 4464 |
SOCS1 | 2.6 | 776 |
IL-1A (IL-1α) | 0.2 | -708 |
IL-1B (IL-1β) | 0.1 | -4738 |
IL-1RN (IL-1ra) | 6.4 | 2211 |
IL-10 | 1.9 | 364 |
IL-10RA (IL-10R) | 2.4 | 1145 |
IL-27 | 1.8 | 250 |
IL-8 | 0.3 | -15409 |
CXCL1 | 0.5 | -167 |