Skip to main content
Figure 1 | Journal of Neuroinflammation

Figure 1

From: Atorvastatin prevents age-related and amyloid-β-induced microglial activation by blocking interferon-γ release from natural killer cells in the brain

Figure 1

Age related inflammatory changes in the brain. A, MHCII mRNA B, CD11b mRNA C, IFNγ mRNA expression, and D, IFNγ concentration were significantly increased in hippocampal tissue prepared from aged compared with young rats (*p < 0.05; **p < 0.01; student's t-test for independent means; n = 5-7). E, IFNγ (50 ng/ml) significantly increased MHCII mRNA and F, CD11b mRNA in cultured glia in vitro.

Back to article page

Journal of Neuroinflammation

ISSN: 1742-2094