Figure 5From: Contribution of complement activation pathways to neuropathology differs among mouse models of Alzheimer's disease C4 is highly expressed in the plaques of Arctic and Tg2576 models but absent in the 3xTg model. C4 immunostaining (brown) in the Arc48 mouse hippocampus at 9 m (top) and Tg2576 cortex at 18 m (middle), and 3xTg subiculum at 18 m (bottom). Colocalization of C4 (red) with thioflavine (green) (top inset) in Arc48 model. Scale bar: 50 um.Back to article page