Figure 7
From: IFN-γ protects from lethal IL-17 mediated viral encephalomyelitis independent of neutrophils
Alterations in chemokines, MMPs and GM-CSF mRNA do not correlate with IL-17-mediated mortality. (A) mRNA expression analyzed in the CNS of naïve mice, infected control mice, and SCID recipients of WT or GKO CD4+ T cells at day eight p.i. Data represent the mean (±SEM) of four individual mice per group (B) MMP9, MMP3, MMP12 and GM-CSF mRNA expression measured in the CNS of naïve, controls, infected SCID recipients of WT, GKO or GKO + anti-IL-17 CD4+ T cells at day eight p.i.. Data are representative of the mean (±SEM) of four individual mice per group.