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Figure 1 | Journal of Neuroinflammation

Figure 1

From: The enteric bacterial metabolite propionic acid alters brain and plasma phospholipid molecular species: further development of a rodent model of autism spectrum disorders

Figure 1

Number of horizontal movements (A), number of vertical movements (B), counterclockwise revolutions (C), clockwise revolutions (D), number of stereotypic movements (E), horizontal movement time (F), and total distance travelled (G), representing abnormal animal behavior following ICV infusions with PPA and PBS. Animals received ICV infusions of PPA ( n = 12) and PBS ( n = 12) twice a day for 7 consecutive days. Behavioral measurements were monitored immediately after each infusion over 30 min. Values represent means ± SE over 7 days. Bars accompanied by asterisks indicate significant difference between treatments at LSD = 0.05, n = 12 per treatment group. PBS, phosphate buffered saline solution; PPA, propionic acid.

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Journal of Neuroinflammation

ISSN: 1742-2094