Figure 4From: IgG glycan hydrolysis by EndoS inhibits experimental autoimmune encephalomyelitis EndoS inhibits peripheral complement activation in EAE mice. (A) Serum complement activation or consumption of complement components C1q, C3, and C9 was evaluated by SDS-PAGE analysis of sera from EndoS- and PBS- treated WT mice (n = 3 per group) at the indicated time after immunization. (B) Relative serum expression of complement components C1q, C3, and C9 (n = 3 independent mice per group) was expressed as arbitrary units of density of bands (intensity/mm2).Back to article page