Figure 2

Intravenous immunoglobulin injection increases MPTP-related weight loss and lethality. Lethality and weight loss rate were monitored throughout the experiment. (A) Mortality rate induced by MPTP treatment was higher in the intravenous immunoglobulin (IVIg) group. (B) Weight and (C) weight variation of the animals excluding all the mice that died before the end of the protocol. Data are presented as mean ± standard error of the mean of 12 to 15 animals. Statistical analysis: (A) log-rank test was performed to compare survival curves, *P <0.05 MPTP-IVIg versus vehicle groups. (B),(C) One-way analysis of variance followed by Tukey’s multiple comparison test, ^# P <0.05 MPTP-IVIg versus vehicle-IVIg group, ^ω P <0.05 MPTP-IVIg versus MPTP-control group.