Figure 2
Post hoc test. Thresholds were set at a corrected P <0.05, determined by Monte Carlo stimulation. (A) Compared with controls group, aMCI group showed increased ALFF in right Pcu/calcarine, while decreased ALFF in left inferior frontal gyrus and superior/middle temporal lobe (yellow: aMCI >control, blue: aMCI <control). (B) Compared with CT genotype, CC genotype showed increased ALFF in left middle/inferior frontal gyrus, and compared with TT genotype, CC genotype also showed increased ALFF in right medial/superior frontal gyrus and right anterior cingulum, while there were no significance between CT and TT genotype (yellow: CC >CT, blue: CC >TT). (C) Further analysis of interaction between groups and genotypes found that both in aMCI and control groups, CC genotype showed significant higher ALFF than CT/TT genotype. The ALFF value for each genotype in controls group was higher than that in aMCI group based on visual comparisons (no significant difference in statistics). *P <0.05.