Figure 3
From: Inflammatory monocytes damage the hippocampus during acute picornavirus infection of the brain
Flow cytometric scatter characteristics of brain-infiltrating leukocytes (BILs) from acutely infected mice. BILs collected from Theiler's murine encephalomyelitis virus (TMEV)-infected mice at 18 hpi were gated by forward scatter (FSC) and side scatter (SSC) profiles into three distinct populations (A). Fraction 1 corresponded to the CD45hiCD11b+++1A8+ neutrophil fraction (B). Fraction 2 corresponded to the CD45hiCD11b++Gr1+ inflammatory monocyte population (C). Fraction 3 contained only CD45midCD11b+Gr1-1A8- microglia (resident macrophages) (D). Results are representative of three mice.