Figure 3
From: The NALP3 inflammasome is involved in neurotoxic prion peptide-induced microglial activation
Exposure of lipopolysaccharide-primed BV2 microglia to PrP106-126 increases mRNA expression of NACHT, LRR and PYD domains-containing protein (NALP)3 and ASC. Measurement by quantitative PCR of the mRNA expression of (a) NALP3 and (b) ASC in BV2 microglia at the indicated time points after exposure to PrP106-126. Data were performed in triplicate and expressed as the mean ± SD, and are representative of three separate experiments. *P < 0.05, significantly different from control under the same experimental conditions.