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Figure 3 | Journal of Neuroinflammation

Figure 3

From: Amyloid β peptide-induced inhibition of endothelial nitric oxide production involves oxidative stress-mediated constitutive eNOS/HSP90 interaction and disruption of agonist-mediated Akt activation

Figure 3

Effects of Aβ peptides (Aβ25–35/Aβ1–42 = active, Aβ35–25/Aβ42–1 = reverse, inactive) on superoxide anion production in BAECs assessed by dichloro-dihydrofluoresceindiacetate (DHCF-DA) fluorimetric assay. Some samples were pre-treated with 2 mM of the anti-oxidant N-acetyl-cysteine (NAC) to determine assay specificity. (*P < 0.001 versus control, n = 6).

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