Fig. 5
From: Pyrrolidine dithiocarbamate activates the Nrf2 pathway in astrocytes
Effect of PDTC and Aβ co-treatment on Nrf2 target genes in primary astrocytes and neurons. a HO-1 and b GCLM mRNA expression levels were measured by quantitative RT-PCR from primary adult astrocyte cultures and hippocampal neuron cultures after 24 h treatment with 5 μM Aβ(1-42) with or without co-treatment with 1 μM PDTC. The mRNA expression levels are presented as mean relative expression normalized to β-actin ± SD. *p < 0.05; **p < 0.001 relative to corresponding control; a p < 0.001 relative to PDTC condition