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Fig. 2 | Journal of Neuroinflammation

Fig. 2

From: Multiallelic copy number variation in the complement component 4A (C4A) gene is associated with late-stage age-related macular degeneration (AMD)

Fig. 2

Association analysis of multiallelic complement C4A (a), C4B (b), and total C4 (c) copy numbers in AMD. Multivariate logistic regression models, adjusted for age and gender, were fitted for C4A, C4B, and total C4 copy number in each study. Log odds ratios and standard errors obtained from each study were combined and a meta-analysis performed assuming a random effects model. The combined estimates for the odds ratios and 95 % confidence intervals (CI) were computed from the random effects model. For C4B CNV, there was statistically significant evidence for heterogeneity of the effect sizes between the studies (P heterogeneity < 0.05)

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Journal of Neuroinflammation

ISSN: 1742-2094