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Fig. 5 | Journal of Neuroinflammation

Fig. 5

From: Impairment of toll-like receptors 2 and 4 leads to compensatory mechanisms after sciatic nerve axotomy

Fig. 5

a, b Gait analysis after sciatic nerve crush in C57BL/6 J and TLR2−/− by using the CatWalk. The paw prints from each animal were obtained before and after the sciatic crush. a Graph of the sciatic functional index (SFI) shows the evaluation of motor recovery up to 8 weeks post-lesion in the experimental groups C57BL/6 J and TLR2−/−. b The intensity of the paw print shows the hind limb paw pressure in both experimental groups. c–f Ultrastructure images of the sciatic nerve from C57BL/6 J and TLR2−/− groups. g Graph of the number of myelinated, unmyelinated and degenerated fibers. Note a greater number of degenerated fibers in knockout mice. Scale bar: 5 μm

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Journal of Neuroinflammation

ISSN: 1742-2094