Fig. 6

Identification of novel epigenetic regulators and inflammatory-related genes in LPS-induced PM cells. a Heat map representation showing the unique and common expression of epigenetic regulators in BV2 cell lines and PM cells after 2- and 4-h LPS stimulation. b UCSC Browser images representing normalized RNA-seq read densities. c Transcript abundance (in read count) was evaluated using RNA-seq in 2- and 4-h LPS-induced BV2 cell lines and PM cells. d Quantitative real-time reverse transcriptase-PCR analysis of the expression of epigenetic regulators showing the markers that were common or unique to PM cells and BV2 cell lines cells that were stimulated with 4-h LPS. Gene expression was normalized to GAPDH transcript levels. *P < 0.01 and **P < 0.001 compared to the control. The data represent three biologically independent experiments. e, f Heat map representation showing the common (left panel) and unique expression (right panel) profiles of novel inflammatory-related genes between BV2 cell lines and PM cells after 2- and 4-h LPS stimulation. g UCSC Browser images representing normalized RNA-seq read densities of novel inflammatory-related genes after 2- and 4-h LPS stimulation in BV2 cell lines and PM cells compared to the controls