Fig. 2

ITPR1-IgG in the CSF. Perfect overlap of the patient IgG from a CSF sample (patient 1) with a commercial antibody to ITPR1 as detected by IHC on a murine cerebellum tissue section. Bound patient IgG is depicted in green (Alexa Fluor® 488) and binding of the commercial anti-ITPR1 antibody in red (Alexa Fluor® 568); yellow indicates areas stained by both antibodies. Cell nuclei were stained by 4',6-diamidino-2-phenylindole (blue)