Fig. 9

Network module output from mummichog analysis of the qualitative and relative quantitative differences in metabolomic profiles of the response to 100 ng/mL cocktail of IL-1, TNF-α, and MCP-1,2 stimulation for 24 h. Feature m/z values and significance measurements were used to predict metabolic activity networks without the use of conventional MS/MS identification workflows. Metabolites are colored blue for negative fold change or red for positive fold change, with the color intensity representing the magnitude of fold change and the size representing the statistical significance (−log₁₀(p value)). a Vascular chamber. b Brain chamber