Journal of Neuroinflammation

Table 2 Activation of human B cells restrains TGF-β1 production

From: Activation of human B cells negatively regulates TGF-β1 production

	Normalized IL-10 MFI		Normalized TGF-β1 MFI		Normalized LAP (TGF-β1) MFI
	CD19⁺ CD27⁻	CD19⁺ CD27⁺	CD19⁺ CD27⁻	CD19⁺ CD27⁺	CD19⁺ CD27⁻	CD19⁺ CD27⁺
Unstimulated	0.67 ± 0.13	0.89 ± 0.11	0.30 ± 0.02	0.34 ± 0.02	3.06 ± 0.36	2.59 ± 0.40
Unstimulated	[0.14–1.10]	[0.55–1.37]	[0.25–0.38]	[0.29–0.44]	[2.18–4.75]	[1.63–4.32]
Stimulated	1.06 ± 0.10	1.70 ± 0.15	0.15 ± 0.01	0.18 ± 0.02	2.38 ± 0.22	2.27 ± 0.31
Stimulated	[0.70–1.42]	[1.25–2.41]	[0.11–0.17]	[0.13–0.22]	[1.78–3.35]	[1.52–3.68]

Values indicate quantification (mean ± SEM) with range (number in parentheses) of cytokine staining in both CD19⁺CD27⁻ and CD19⁺CD27⁺ B cells (n = 6). Geometric mean fluorescence intensities (MFI) were normalized to the isotype control

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