Fig. 4
From: Complex regulation of neutrophil-derived MMP-9 secretion in central nervous system tuberculosis
The Akt pathway regulates neutrophil MMP-9 secretion in TB. a Pre-incubation with PI3-kinase inhibitor LY294002 suppresses MMP-9 secretion with CoMTB. b Representative immunoblots to detect p-Akt in neutrophils infected with M.tb show increased phosphorylation with corresponding densitometric analysis. c Pre-incubation with PI3-kinase inhibitor LY does not affect MMP-9 secretion after M.tb infection. Bars represent mean ± s.d and are representative of at least two independent experiments performed in triplicate. *P < 0.05; **P < 0.01