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Table 3 Correlation of piglet neonatal serum cytokine levels with cerebral metabolite ratios assessed by proton-MRS

From: Systemic pro-inflammatory cytokine status following therapeutic hypothermia in a piglet hypoxia-ischemia model

Cytokines

Lac/NAA

Naa/Cr

Lac/Cr

Basal ganglia

White matter

Basal ganglia

White matter

Basal ganglia

White matter

Coef

p Value

Coef

p Value

Coef

p Value

Coef

p Value

Coef

p Value

Coef

p Value

IL-1β

0.51

<0.001

0.42

0.003

−0.33

0.02

−0.31

0.004

0.51

<0.001

0.4

0.005

IL-4

−0.01

0.96

0.06

0.71

0.22

0.13

0.18

0.24

0.06

0.68

0.15

0.30

IL-6

0.02

0.87

0.15

0.30

0.18

0.21

0.06

0.71

0.09

0.55

0.22

0.14

IL-8

0.25

0.09

0.28

0.05

−0.18

0.21

−0.23

0.12

0.23

0.11

0.25

0.10

IL-10

0.46

<0.001

0.50

<0.001

−0.37

0.01

−0.40

0.005

0.42

0.003

0.46

0.001

TNF-α

0.13

0.38

0.09

0.53

0.02

0.88

−0.01

0.93

0.17

0.25

0.07

0.63

  1. Bold p values indicate significance at p < 0.05
  2. Statistical association based on Spearman’s rank correlation