Fig. 2
From: Lack of interleukin-13 receptor α1 delays the loss of dopaminergic neurons during chronic stress
Acute restraint stress induces central production of IL-13 in the substantia nigra. a Semi-quantitative RT-PCR performed on RNA extracted from the SN of mice treated with acute RS showed that compared with the level of control animals, arbitrarily fixed to 1 (n = 8), levels were 0.37 ± 0.032, p > 0.99; 0.90 ± 0.186, p > 0.99; 3.89 ± 1.545, p = 0.04 and 2.63 ± 0.704, p = 0.74 at 1, 3, 6, and 8 h, respectively, n = 6. b Semi-quantitative RT-PCR assessing expression of IL-13Rα1 on same samples described in figure A shows no difference in all time points compared to control condition (p > 0.99 at control, 1, 3, 6, and 8 h). c Protein quantification in the SN shows upregulation of IL-13 during restraint stress (IL-13 in pg/mg total protein: 2.644 ± 0.50 control; 5.607 ± 2.793 at 1 h RS, p > 0.99;7.128 ± 3.123, at 3 h, p = 0.679; 8.857 ± 1.361 at 6 h RS, p = 0.1612, and 11.7 ± 3.195 at 8 h RS, p = 0.0342)