Fig. 2

A Neurologic deficit score (NDS) at 3 h and 24 h after treatment in sham and stroke aged mice with cromolyn or vehicle treatment shows significant improvement in post-stroke recovery and outcomes. Two-way ANOVA and Turkey’s multiple comparison show the statistical significance among the groups (n = 12–15 per group). h—hours, PS—post-stroke, crom—cromolyn. B Digigait paw positioning at 3 days PS. The motility activity is significantly improved 3 days after stroke in the cromolyn-treated mice compared to the vehicle-treated mice (n = 5–10). C Relative infarct volume 3 days after stroke in cromolyn-treated and PBS-treated mice. Cromolyn-treated mice had no significant changes in infarct volume in both cortex and striatum compared to the PBS group (striatum showed a trend in reduced infarct volume, n = 6–7, t Student analysis). Data are expressed as mean ± SEM, as well as individual values, and are obtained from > 4 independent experiments at various times. *P < 0.05, **P < 0.01, ***P < 0.001