Skip to main content
Fig. 3 | Journal of Neuroinflammation

Fig. 3

From: Transient immune activation without loss of intraepidermal innervation and associated Schwann cells in patients with complex regional pain syndrome

Fig. 3

Intraepidermal Schwann cells in human glabrous skin. Skin biopsies from the index finger at the border between glabrous and hairy skin were immunolabelled. A, B, C Representative images of intraepidermal Schwann cell processes (S100+), intraepidermal nerve fibres (IENFs, PGP9.5+), Langerhans cells (CD207+), and the epidermal-dermal border (collagen IV, Coll IV+). Nerve fibres crossing the epidermal-dermal border (dashed lines) were counted as IENF (arrows), S100-positive Schwann cell processes co-localized with them (arrowheads). S100-positive Langerhans cells close to the epidermal-dermal border were excluded (asterisk). Scale bars = 50 µm

Back to article page

Journal of Neuroinflammation

ISSN: 1742-2094