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Table 1 Summary of demographic and clinical data of healthy control and CRPS study cohorts

From: Transient immune activation without loss of intraepidermal innervation and associated Schwann cells in patients with complex regional pain syndrome

 

Acute CRPS n = 19

Chronic CRPS n = 6

HC n = 25

Age (years)

54 ± 9

40 ± 13*

51 ± 11

Sex (female in %)

74%

100%

80%

CRPS type I

58% (n = 11)

83% (n = 5)

 

Initially warm

63% (n = 12)

50% (n = 3)

 

Time since event (months)

5.2 ± 2.8

19.0 ± 4.8

 

Time since diagnosis (months)

2.1 ± 2.5

7.3 ± 8.6

 

Mean pain (NRS)

5.3 ± 2.2

5.0 ± 2.2

 

Max pain (NRS)

7.4 ± 2.2

7.2 ± 3.0

 

Allodynia

37% (n = 7)

17% (n = 1)

 

Hyperalgesia

53% (n = 10)

66% (n = 4)

 

Oedema

79% (n = 15)

66% (n = 4)

 

Skin temp (Δ°C)

-0.3 ± 1.4

0.5 ± 0.9

 

CSS1

10.4 ± 1.9

10.7 ± 2.1

 

NPSI2

30.4 ± 22.2 (n = 16)

35.5 ± 28.1

3.2 ± 4.8 (n = 20)

STAI-T3

45.0 ± 11.0

38.7 ± 17.3

31.7 ± 7.2 (n = 24)

BDI-II4

14.6 ± 10.4 (n = 17)

9.8 ± 9.5

3.9 ± 4 (n = 24)

DASH5

62.4 ± 20.9 (n = 18)

37.7 ± 23.1

3.5 ± 4.1 (n = 23)

  1. 1CRPS severity score, range 0–17
  2. 2Neuropathic pain symptom inventory, range 0–100
  3. 3State-Trait anxiety inventory trait anxiety subscale, range 20–80
  4. 4Beck depression inventory II, range 0–63
  5. 5Disability of arm, shoulder and hand, range 0–100. CRPS: complex regional pain syndrome; HC: healthy control; *p < 0.05 compared with acute CRPS group