Fig. 2
From: Autophagy dysfunction contributes to NLRP1 inflammasome-linked depressive-like behaviors in mice
Effects of different time courses of CSDS on NLRP1 inflammasome and PI3K/AKT/mTOR signaling activation in mice. A–C Representative immunoreactive bands and statistical results show that CSDS exposure increased the expression of hippocampal NLRP1 (A), ASC (B), caspase-1 (C), IL-6 (D), IL-1β (E), TNF-α (F), p-PI3K (G), p-AKT (H) and p-mTOR (I) in a time-dependent manner. Data represented the mean ± SEM. n = 6, *p < 0.05, **p < 0.01 vs. control group