Fig. 2

T. gondii infection leads to decreased body weight and an enlarged spleen in both sexes. In both males (A) and females (B), T. gondii mice weighed less than Vehicle mice 6-weeks after infection (i.e., time of CCI/sham injury), as well as at 12- (i.e., at behavioral testing) and 18-weeks post-CCI/sham injury. Both male and female T. gondii mice had increased spleen weight compared to Vehicle mice at 2-h (C, D), 24-h (E, F) and 1-week (G, H) post-injury. Only the male T. gondii mice had increased spleen weight compared to their Vehicle counterparts at 18-weeks post injury (I, J). Data displayed as mean ± SD. **p ≤ 0.01. ***p ≤ 0.001