Table 1 Cell, glutamate pathway, neuroinflammatory, oxidative stress, blood–brain barrier (BBB) and reference genes analyzed via RT-PCR

Reference

Neuroinflammation

 1

YWHAZ

Mm01722325_m1

 26

TSPO

Mm00437828_m1

 2

ACTB

Mm00607939_s1

 27

NLRP3

Mm00840904_m1

 3

GAPDH

Mm99999915_g1

 28

IL1β

Mm00434228_m1

 4

UBC

Mm02525934_g1

 29

IL2

Mm00434256_m1

Cell markers

 30

IL6

Mm00446190_m1

 5

GFAP

Mm01253033_m1

 31

IL10

Mm00439616_m1

 6

CD45

Mm01293577_m1

 32

IL12p40

Mm01288989_m1

 7

CD86

Mm00444543_m1

 33

IL33

Mm00505403_m1

 8

CD206

Mm01329362_m1

 34

TNFα

Mm99999068_m1

 9

TREM2

Mm04209424_g1

 35

CSF1/ M-CSF

Mm00432688_m1

 10

CCR5

Mm01216171_m1

 36

CSF2/ GM-CSF

Mm00438328_m1

 11

IBA1

Mm00479862_g1

 37

CXCL10

Mm00445235_m1

 12

TMEM119

Mm00525305_m1

 38

IFNγ

Mm00801778_m1

 13

GATA3

Mm00484683_m1

 39

TGFβ/ TGIF1

Mm01227699_m1

 14

CXCR3

Mm00438259_m1

 40

ARG1

Mm00475988_m1

 15

STAT1

Mm01257286_m1

 41

CCL2

Mm00441242_m1

 16

SOCS1

Mm00782550_s1

 42

CCL4

Mm00443111_m1

 17

FOXP3

Mm00475162_m1

 43

CCL5

Mm01302427_m1

 18

MAP2

Mm00485231_m1

 44

CCL12

Mm01617100_m1

Glutamate pathway

Oxidative stress

 19

GLT1

Mm01275814_m1

 45

IDO1

Mm00492586_m1

 20

GLAST

Mm01306917_g1

 46

NOS2

Mm00440502_m1

 21

GAD1

Mm04207432_g1

 47

CYBB

Mm01287743_m1

 22

PHGDH

Mm01623589_g1

BBB disruption/Vascular health

 23

GLUL

Mm00725701_s1

 48

OCLN

Mm00500912_m1

 24

GRIN2B

Mm00433820_m1

 49

TJP1/ZO1

Mm00493699_m1

 25

PPARγ

Mm01184322_m1

 50

ICAM1

Mm00516023_m1

 51

HIF1A

Mm00468869_m1

 52

VEGFA

Mm00437306_m1

 53

SYNAPTOPHYSIN

Mm00436850_m1