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Fig. 10 | Journal of Neuroinflammation

Fig. 10

From: Increased regulatory activity of intestinal innate lymphoid cells type 3 (ILC3) prevents experimental autoimmune encephalomyelitis severity

Fig. 10

ILC3 counteracts CNS autoimmunity. ILC3 in the small intestine gut lamina propria are stimulated through Ffar2 to limit activity of encephalitogenic cells within the lamina propria, but also in other lymph organs. As the consequence of their actions CNS autoimmunity is downregulated in EAE. Future studies should reveal if such mechanism is relevant for multiple sclerosis

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Journal of Neuroinflammation

ISSN: 1742-2094