Fig. 9

Acetate inhibits colonic tissue fibrosis in SHRs. A, representative micrographs from hematoxylin-eosin (HE) and Masson’s trichrome staining assays of the colonic tissues. Quantitative analysis of the thickness of the muscular layer (B), villi length (C) and goblet cells/villi (D) on HE-stained sections of the colon. n = 10 for each group. E, quantitative analysis of fibrotic area on Masson’s-stained sections of the colon. n = 6 for each group. F, the permeability of the colonic mucosa to the bloodstream was evaluated by measuring the plasma concentration of FITC-dextran (4 kDa). n = 4 for each group. * P < 0.05, ** P < 0.01