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Fig. 3 | Journal of Neuroinflammation

Fig. 3

From: Immunotherapy with an antibody against CD1d modulates neuroinflammation in an α-synuclein transgenic model of Lewy body like disease

Fig. 3

Flow cytometry analysis of T cells in blood and peripheral tissues of ⍺-synuclein transgenic mice treated with CD1d. (A) Representative flow cytometry plots of CD1d-tet and TCRβ+ expression in the spleen; (B–D) graphs of the frequency of NKT cells of CD45+CD11b− cells in the spleen, liver and blood of non-tg and ⍺-syn tg mice treated with IgG or anti-CD1d. (E) Representative flow cytometry plots of TCRβ+ CD45+ expression in spleen; (F–H) graphs of frequency of CD4+ cells in the spleen, liver and blood respectively and (I–K) CD8+ cells in the spleen, liver and blood respectively. n = 4 mice per group. Statistical significance determined by two-way ANOVA with post-hoc Tukey; *, p ≤ 0.05

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Journal of Neuroinflammation

ISSN: 1742-2094