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Fig. 9 | Journal of Neuroinflammation

Fig. 9

From: Immunotherapy with an antibody against CD1d modulates neuroinflammation in an α-synuclein transgenic model of Lewy body like disease

Fig. 9

Behavioral analysis of ⍺-synuclein transgenic mice treated with anti-CD1d. (A–D) Rotarod motor testing in non-tg and ⍺-syn tg mice treated with IgG or anti-CD1d showing latency to fall over five trial per day for a total of four days. (E–G) Open field testing showing total path, total counts, and time in the center of the field in non-tg and ⍺-syn tg mice treated with IgG or anti-CD1d. (H) Wire hang test showing time expended suspending in the wire in day 1 and day 2 of the test in IgG and anti-CD1d treated non-tg and ⍺-syn tg mice. Statistical significance determined by two-way ANOVA with post-hoc Tukey; *, p ≤ 0.05

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Journal of Neuroinflammation

ISSN: 1742-2094