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Table 3 Comparing detailed NCS data between patients with MMN with IgM anti-GM2 antibodies (n = 7) and without (n = 9)

From: IgM anti-GM2 antibodies in patients with multifocal motor neuropathy target Schwann cells and are associated with early onset

CMAPs/SNAPs/F-waves

GM2 +

GM2 -

p

Velocities (m/s)

GM2 +

GM2 -

p

Median nerve

       

DML

4.2 (0.65)

4.1 (0.83)

0.86

-

-

-

-

CMAP

Wrist

8.7 (4.2)

7.5 (11.3)

0.8

-

-

-

-

 

Elbow

6.0 (7.2)

6.0 (7.8)

0.92

Forearm

48 (15.5)

51 (19.8)

0.85

 

Axilla

2.9 (4.4)

6.0 (6.9)

0.46

Upper arm

50 (11)

55 (20.5)

0.40

 

Erb’s point

3.3 (6.4)

6.5 (6.5)

0.59

Erb’s point

68 (23.8)

67 (10)

0.63

SNAP

Wrist

17.1 (13.2)

20.8 (15.9)

0.88

SNAP velocity

52 (3)

55 (7)

0.25

F-wave latency

35.1 (15.1)

33.2 (7.1)

0.70

-

-

-

-

Ulnar nerve

       

DML

3.5 (1.1)

3.4 (0.53)

0.55

-

-

-

-

CMAP

Wrist

6.4 (3.0)

7.9 (9.7)

0.58

-

-

-

-

 

Sulcus (distal)

2.9 (4.9)

7.8 (9.0)

0.58

Forearm

52 (25.8)

54 (9)

0.31

 

Sulcus (proximal)

3.0 (5.5)

7.5 (9.0)

0.49

Sulcus

47 (12.3)

50 (12.3)

0.43

 

Axilla

2.7 (4.7)

4.4 (6.9)

0.47

Upper arm

49 (25)

56 (33.5)

0.80

 

Erb’s point

1.9 (4.1)

4.5 (6.2)

0.42

Erb’s point

63 (23)

64 (12)

0.42

SNAP

Wrist

25 (22.9)

10 (6.7)

0.0074*

SNAP

51 (2.8)

48 (6.3)

0.38

F-wave latency

36.1 (26.9)

31.7 (7.3)

0.65

-

-

-

-

Radial nerve

       

SNAP

Wrist

17 (15.4)

14.9 (13.5)

0.27

SNAP velocity

53 (4)

52 (4.3)

0.66

Deep peroneal nerve

       

DML

4.1 (0.7)

5.1 (1.9)

0.007

-

-

-

-

CMAP

Ankle

3.6 (5.6)

3.7 (4.1)

0.98

-

-

-

-

 

Fibular head (distal)

2.8 (4.4)

2.9 (4.2)

0.63

Lower leg

46 (7)

42 (6)

0.26

 

Fibular head (proximal)

2.7 (3.7)

2.8 (4.1)

0.63

Fibular head

46 (5)

47 (6)

0.79

F-wave latency

57.3 (11.9)

59.7 (9.3)

0.24

-

-

-

-

Tibial nerve

       

DML

5.1 (1.0)

4.9 (1.8)

0.65

-

-

-

-

CMAP

Ankle

6.5 (6.2)

9 (8.2)

0.65

-

-

-

-

 

Knee

3.4 (5.4)

4.4 (6.2)

0.59

Lower leg

44 (4)

45 (2)

1.00

F-wave latency

58.9 (18)

60.3 (5.0)

0.89

-

-

-

-

Sural nerve

       

SNAP

9 (3.5)

12 (9.5)

0.52

SNAP velocity

46 (8)

48 (7)

0.28

  1. * Statistically significant at p-value < 0.05
  2. CMAP Compound muscle action potential, DML Distal motor latency, MMN Multifocal motor neuropathy, NCS Nerve conduction studies, SNAP Sensory nerve action potential