Fig. 8

Flow cytometry analysis of CD11b⁺ cells from the striatum and in the ventral midbrain after MPTP intoxication. (A) Gating strategy for CD11b⁺ cell subsets differentiated based on the level of CD45 expression, CD11b⁺CD45^low and CD11b⁺CD45^high, and Ki67 expression. The fraction of CD11b⁺CD45^low and CD11b⁺CD45^high cells out of viable cells and frequency of Ki67⁺ cells in these populations were analyzed in the striatum and midbrain of (B) sMPTP, (C) ecMPTP and (D) cMPTP mice. Data represent the mean ± 95% CI from 6 to 8 animals/group. Statistical analysis: (B-D) t-test for data following a normal distribution and Mann-Whitney test for data not following a normal distribution. *p < 0.05, **p < 0.01