Fig. 9

Flow cytometry analysis of lymphocyte infiltration in the striatum and in the ventral midbrain after MPTP intoxication. (A) Representative gating strategy to select CD11b⁻CD45^high population, and then CD4⁺ and CD8⁺ cells in cells suspension prepared from the ventral midbrain. Fraction of CD4⁺ and CD8⁺ cells out of viable cells in the striatum and midbrain of (B) sMPTP, (C) ecMPTP and (D) cMPTP mice. Data represent the mean ± 95% CI from 6 animals/group. Statistical analysis: (B-D) t-test for data following a normal distribution with Welch correction when variances differed significantly. Mann-Whitney test for data not following a normal distribution. *p < 0.05