Table 1 p values corresponding to the GSEA analysis performed to compare striatal and midbrain differentially displayed genes in CD11b+ cells with signatures that represent different microglial states
From: Nigrostriatal degeneration determines dynamics of glial inflammatory and phagocytic activity
sMPTP | cMPTP | ||||
|---|---|---|---|---|---|
Signatures | Striatum | Midbrain | Striatum | Midbrain | |
MGnD | Up | 0.945 | 0.625 | 0.423 | 0.127 |
Down | 0.476 | 0.036* | 0.234 | 0.226 | |
DAM | Up | 0.093 | 0.985 | 0.005** | 0.057 |
Down | < 0.001*** | < 0.001*** | 0.004** | < 0.001*** | |
Phagocytic microglia | Up | 0.001** | 0.746 | < 0.001*** | < 0.001*** |
Down | 0.051 | 0.279 | 0.252 | 0.028* | |
Phagocytosis (GOBP) | 0.494 | 0.836 | 0.029* | 0.075 | |