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Figure 4 | Journal of Neuroinflammation

Figure 4

From: Neuronal oxidative damage and dendritic degeneration following activation of CD14-dependent innate immune response in vivo

Figure 4

Dendritic arbor in CA1 pyramidal neurons of hippocampus from knockout mice. Adult (6 to 8 week old) wt C57Bl/6, CD14-/-, or MyD88-/- mice received ICV saline 24 hr prior to sacrifice. Tissue sections of hippocampus and surrounding structures were processed for Golgi stain and then evaluated by Neurolucida. Data are dendrite length for CA1 hippocampal pyramidal neurons (n > 15 neurons for each group). One-way ANOVA had P < 0.0001 with Bonferroni-corrected repeated pair comparisons having *P < 0.001 for wt vs. CD14-/- and CD14-/- vs. MyD88-/-.

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Journal of Neuroinflammation

ISSN: 1742-2094