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Journal of Neuroinflammation

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  1. Content type: Research

    Evidence suggests that brain infiltration of lymphocytes contributes to acute neural injury after cerebral ischemia. However, the spatio-temporal dynamics of brain-infiltrating lymphocytes during the late stag...

    Authors: Yan Feng, Shiwei Liao, Changjuan Wei, Dongmei Jia, Kristofer Wood, Qiang Liu, Xiaoying Wang, Fu-Dong Shi and Wei-Na Jin

    Citation: Journal of Neuroinflammation 2017 14:248

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  2. Content type: Research

    N-arachidonoylphenolamine (AM404), a paracetamol metabolite, is a potent agonist of the transient receptor potential vanilloid type 1 (TRPV1) and low-affinity ligand of the cannabinoid...

    Authors: Soraya Wilke Saliba, Ariel R. Marcotegui, Ellen Fortwängler, Johannes Ditrich, Juan Carlos Perazzo, Eduardo Muñoz, Antônio Carlos Pinheiro de Oliveira and Bernd L. Fiebich

    Citation: Journal of Neuroinflammation 2017 14:246

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  3. Content type: Research

    The tachykinin substance P (SP) is recognized to exacerbate inflammation at peripheral sites via its target receptor, neurokinin 1 receptor (NK-1R), expressed by leukocytes. More recently, SP/NK-1R interaction...

    Authors: Amanda R. Burmeister, M. Brittany Johnson, Vinita S. Chauhan, Megan J. Moerdyk-Schauwecker, Ada D. Young, Ian D. Cooley, Alejandra N. Martinez, Geeta Ramesh, Mario T. Philipp and Ian Marriott

    Citation: Journal of Neuroinflammation 2017 14:245

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  4. Content type: Research

    Asymmetric dimethylarginine (ADMA)––the most potent endogenous NO-synthase inhibitor, has been regarded as mediator of endothelial dysfunction and oxidative stress. Considering experimental data, levels of ADM...

    Authors: Hans Worthmann, Na Li, Jens Martens-Lobenhoffer, Meike Dirks, Ramona Schuppner, Ralf Lichtinghagen, Jan T. Kielstein, Peter Raab, Heinrich Lanfermann, Stefanie M. Bode-Böger and Karin Weissenborn

    Citation: Journal of Neuroinflammation 2017 14:247

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  5. Content type: Research

    Neuroinflammation and a systemic inflammatory reaction are important features of perinatal asphyxia. Neuroinflammation may have dual aspects being a hindrance, but also a significant help in the recovery of th...

    Authors: Anna Bajnok, László Berta, Csaba Orbán, Gábor Veres, Dénes Zádori, Hajnalka Barta, Ünőke Méder, László Vécsei, Tivadar Tulassay, Miklós Szabó and Gergely Toldi

    Citation: Journal of Neuroinflammation 2017 14:244

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  6. Content type: Research

    The production of reactive oxygen species (ROS) during pneumococcal meningitis (PM) leads to severe DNA damage in the neurons and is the major cause of cell death during infection. Hence, the use of antioxidan...

    Authors: Leonam G. Coutinho, Ana Helena Sales de Oliveira, Matthias Witwer, Stephen L. Leib and Lucymara F. Agnez-Lima

    Citation: Journal of Neuroinflammation 2017 14:243

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  7. Content type: Research

    Despite effectiveness of the combined antiretroviral therapy, HIV-1 persists in long-lived latently infected cells. Consequently, new therapeutic approaches aimed at eliminating this latent reservoir are curre...

    Authors: Alizé Proust, Corinne Barat, Mathieu Leboeuf, Jean Drouin and Michel J. Tremblay

    Citation: Journal of Neuroinflammation 2017 14:242

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  8. Content type: Research

    Methamphetamine (METH) is a commonly abused drug that may result in neurotoxic effects. Recent studies have suggested that involvement of neuroinflammatory processes in brain dysfunction is induced by misuse o...

    Authors: Ji-Hyun Park, Young Ho Seo, Jung-Hee Jang, Chul-Ho Jeong, Sooyeun Lee and Byoungduck Park

    Citation: Journal of Neuroinflammation 2017 14:240

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  9. Content type: Research

    Due to its neurotoxic properties, oligomeric alpha-synuclein (α-syn) has been suggested as an attractive target for passive immunization against Parkinson’s disease (PD). In mouse models of PD, antibody treatm...

    Authors: Gabriel Gustafsson, Veronica Lindström, Jinar Rostami, Eva Nordström, Lars Lannfelt, Joakim Bergström, Martin Ingelsson and Anna Erlandsson

    Citation: Journal of Neuroinflammation 2017 14:241

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  10. Content type: Research

    The NLRP3 inflammasome activation and neuroinflammation are known to be involved in the pathology of depression, whereas autophagy has multiple effects on immunity, which is partly mediated by the regulation o...

    Authors: Pei Jiang, Yujin Guo, Ruili Dang, Mengqi Yang, Dehua Liao, Huande Li, Zhen Sun, Qingyan Feng and Pengfei Xu

    Citation: Journal of Neuroinflammation 2017 14:239

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  11. Content type: Research

    Microglia are resident myeloid cells of the central nervous system (CNS) that are maintained by self-renewal and actively participate in tissue homeostasis and immune defense. Under the influence of endogenous...

    Authors: Giovanna Pepe, Marcella De Maglie, Lucia Minoli, Alessandro Villa, Adriana Maggi and Elisabetta Vegeto

    Citation: Journal of Neuroinflammation 2017 14:236

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  12. Content type: Research

    Ischemic stroke is one of the main causes of death and disability worldwide. It is caused by the cessation of cerebral blood flow resulting in the insufficient delivery of glucose and oxygen to the neural tiss...

    Authors: Hiramani Dhungana, Mikko T. Huuskonen, Merja Jaronen, Sighild Lemarchant, Humair Ali, Velta Keksa-Goldsteine, Gundars Goldsteins, Katja M. Kanninen, Jari Koistinaho and Tarja Malm

    Citation: Journal of Neuroinflammation 2017 14:237

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  13. Content type: Research

    Viral encephalitis is a dangerous compromise between the need to robustly clear pathogen from the brain and the need to protect neurons from bystander injury. Theiler’s murine encephalomyelitis virus (TMEV) in...

    Authors: Charles L. Howe, Reghann G. LaFrance-Corey, Emma N. Goddery, Renee K. Johnson and Kanish Mirchia

    Citation: Journal of Neuroinflammation 2017 14:238

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  14. Content type: Research

    Multiple sclerosis (MS) is a demyelinating and degenerative disease of the central nervous system. Normally, demyelination is followed by remyelination, which requires repopulation of a demyelinated area by ol...

    Authors: Ilona B. Bruinsma, Marie van Dijk, Claire Bridel, Timothy van de Lisdonk, Sanne Q. Haverkort, Tessel F. Runia, Lawrence Steinman, Rogier Q. Hintzen, Joep Killestein, Marcel M. Verbeek, Charlotte E. Teunissen and Brigit A. de Jong

    Citation: Journal of Neuroinflammation 2017 14:235

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  15. Content type: Research

    It has been shown that chronic stress-induced depression is associated with exaggerated inflammatory response in the brain. Alpha7 nicotinic acetylcholine receptors (α7nAChRs) regulate the cholinergic anti-inf...

    Authors: Dan Zhao, Xulin Xu, Linna Pan, Wei Zhu, Xiaopei Fu, Lianjun Guo, Qing Lu and Jian Wang

    Citation: Journal of Neuroinflammation 2017 14:234

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  16. Content type: Research

    Neuroinflammation, which ultimately leads to neuronal loss, is considered to play a crucial role in numerous neurodegenerative diseases. The neuroinflammatory process is characterized by the activation of glia...

    Authors: Yi-wei Wang, Qin Zhou, Xiang Zhang, Qing-qing Qian, Jia-wen Xu, Peng-fei Ni and Yan-ning Qian

    Citation: Journal of Neuroinflammation 2017 14:233

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  17. Content type: Review

    Inflammatory neuropathies are rare autoimmune-mediated disorders affecting the peripheral nervous system. Considerable progress has recently been made in understanding pathomechanisms of these disorders which ...

    Authors: David Schafflick, Bernd C. Kieseier, Heinz Wiendl and Gerd Meyer zu Horste

    Citation: Journal of Neuroinflammation 2017 14:232

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  18. Content type: Research

    MicroRNAs (miRNAs) play a major role in regulating immune responses at post-transcriptional levels. Previously, we have reported fluctuating interlukine-1ß (IL-1ß)/IL-10 ratios produced by peripheral blood mon...

    Authors: Harumi Jyonouchi, Lee Geng, Deanna L. Streck, James J. Dermody and Gokce A. Toruner

    Citation: Journal of Neuroinflammation 2017 14:229

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  19. Content type: Research

    Long-term use of morphine induces analgesic tolerance, which limits its clinical efficacy. Evidence indicated morphine-evoked neuroinflammation mediated by toll-like receptor 4 (TLR4) - NOD-like receptor prote...

    Authors: Jie Qu, Xue-You Tao, Peng Teng, Yan Zhang, Ci-Liang Guo, Liang Hu, Yan-Ning Qian, Chun-Yi Jiang and Wen-Tao Liu

    Citation: Journal of Neuroinflammation 2017 14:228

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  20. Content type: Research

    Spinal cord astrocyte swelling is an important component to spinal cord edema and is associated with poor functional recovery as well as therapeutic resistance after spinal cord injury (SCI). High mobility gro...

    Authors: Lin Sun, Man Li, Xun Ma, Haoyu Feng, Junlai Song, Cong Lv and Yajun He

    Citation: Journal of Neuroinflammation 2017 14:231

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  21. Content type: Research

    Inflammatory responses significantly contribute to neuronal damage and poor functional outcomes following intracerebral hemorrhage (ICH). Soluble epoxide hydrolase (sEH) is known to induce neuroinflammatory re...

    Authors: Chun-Hu Wu, Song-Kun Shyue, Tai-Ho Hung, Shin Wen, Chao-Chang Lin, Che-Feng Chang and Szu-Fu Chen

    Citation: Journal of Neuroinflammation 2017 14:230

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  22. Content type: Research

    Neural precursor cells (NPCs) located in the subventricular zone (SVZ), a well-defined NPC niche, play a crucial role in central nervous system (CNS) homeostasis. Moreover, NPCs are involved in the endogenous ...

    Authors: Evangelia Kesidou, Olga Touloumi, Roza Lagoudaki, Evangelia Nousiopoulou, Paschalis Theotokis, Kyriaki-Nepheli Poulatsidou, Marina Boziki, Evangelia Kofidou, Nickoleta Delivanoglou, Fani Minti, Georgios Hadjigeorgiou, Nikolaos Grigoriadis and Constantina Simeonidou

    Citation: Journal of Neuroinflammation 2017 14:227

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  23. Content type: Research

    Progranulin deficiency due to heterozygous null mutations in the GRN gene are a common cause of familial frontotemporal lobar degeneration (FTLD), while homozygous loss-of-function GRN mutations are thought to be...

    Authors: Terri L. Petkau, Natalia Kosior, Kathleen de Asis, Colúm Connolly and Blair R. Leavitt

    Citation: Journal of Neuroinflammation 2017 14:225

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  24. Content type: Correction

    After publication of the article [1], it has been brought to our attention that several of the authors’ names were formatted incorrectly in the original version of the article. The corrections are listed below –

    Authors: Kyungmin Kim, Byung Ok Kwak, Aram Kwon, Jongseok Ha, Soo-Jin Kim, Sun Whan Bae, Jae Sung Son, Soo-Nyung Kim and Ran Lee

    Citation: Journal of Neuroinflammation 2017 14:226

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    The original article was published in Journal of Neuroinflammation 2017 14:200

  25. Content type: Research

    The aim of the research is to study the human leukocyte antigen (HLA) class II allele frequencies in chronic inflammatory demyelinating polyradiculoneuropathy (CIDP) associated with anti-neurofascin 155 (NF155...

    Authors: Laura Martinez-Martinez, Ma. Cinta Lleixà, Gemma Boera-Carnicero, Andrea Cortese, Jérôme Devaux, Ana Siles, Yusuf Rajabally, Alicia Martinez-Piñeiro, Alejandra Carvajal, Julio Pardo, Emilien Delmont, Shahram Attarian, Jordi Diaz-Manera, Ilaria Callegari, Enrico Marchioni, Diego Franciotta…

    Citation: Journal of Neuroinflammation 2017 14:224

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