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Table 1 Morphometric parameters of the nerve at four weeks after crush injury

From: Critical role of p38 MAPK for regeneration of the sciatic nerve following crush injury in vivo

  Crush side Contralateral side
  p38 +/+ p38 +/− P p38 +/+ p38 +/− P
Axon diameter (μm2) 1.52±0.06 1.37±0.04* <0.05 3.87±1.37 3.75±1.64 N.S.
Axon area (μm2) 5.24±0.36 3.15±0.15** <0.01 10.21±2.34 9.93±2.94 N.S.
Axon number (N) 2850±550 2700±650 N.S. 5800±300 5650±250 N.S.
Axon density (N/mm2) 11500±4100 10150±4650 N.S. 22450±3050 21050±2800 N.S.
G-ratio 0.86±0.05 0.87±0.04 N.S. 0.74±0.03 0.75±0.05 N.S.
Myelin sheath thickness (μm) 0.18±0.06 0.15±0.13* <0.05 0.98±0.29 0.96±0.33 N.S.
  1. N.S., not significant.