Table 1 Morphometric parameters of the nerve at four weeks after crush injury
From: Critical role of p38 MAPK for regeneration of the sciatic nerve following crush injury in vivo
Crush side | Contralateral side | |||||
|---|---|---|---|---|---|---|
p38 +/+ | p38 +/− | P | p38 +/+ | p38 +/− | P | |
Axon diameter (μm2) | 1.52±0.06 | 1.37±0.04* | <0.05 | 3.87±1.37 | 3.75±1.64 | N.S. |
Axon area (μm2) | 5.24±0.36 | 3.15±0.15** | <0.01 | 10.21±2.34 | 9.93±2.94 | N.S. |
Axon number (N) | 2850±550 | 2700±650 | N.S. | 5800±300 | 5650±250 | N.S. |
Axon density (N/mm2) | 11500±4100 | 10150±4650 | N.S. | 22450±3050 | 21050±2800 | N.S. |
G-ratio | 0.86±0.05 | 0.87±0.04 | N.S. | 0.74±0.03 | 0.75±0.05 | N.S. |
Myelin sheath thickness (μm) | 0.18±0.06 | 0.15±0.13* | <0.05 | 0.98±0.29 | 0.96±0.33 | N.S. |