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Table 2 rs187084 polymorphism association with Alzheimer’s disease (AD) according to different genetic models

From: Toll-like receptor 9 promoter polymorphism is associated with decreased risk of Alzheimer’s disease in Han Chinese

SNP Modela Wald OR (95% CI) P P for ApoE interaction
rs187084 D 0.490 0.940 (0.791 to 1.118) 0.484 0.264
  A 2.538 0.906 (0.801 to 1.023) 0.111 0.009
  R 4.459 0.776 (0.613 to 0.982) 0.035 < 0.001
  1. aThe logistic genetic models were defined as follows:
  2. D, dominant model, defined as 1 (GG + GA) versus 0 (AA);
  3. A, additive model, 2 (GG) versus 1 (GA) versus 0 (AA);
  4. R, recessive model, 1 (GG) versus 0 (GA + AA).
  5. P < 0.05 was considered significant.
  6. ApoE, apolipoprotein E ϵ4; CI: confidence interval; OR: odds ratio; SNP, single-nucleotide polymorphism.