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Table 2 rs187084 polymorphism association with Alzheimer’s disease (AD) according to different genetic models

From: Toll-like receptor 9 promoter polymorphism is associated with decreased risk of Alzheimer’s disease in Han Chinese

SNP

Modela

Wald

OR (95% CI)

P

P for ApoE interaction

rs187084

D

0.490

0.940 (0.791 to 1.118)

0.484

0.264

 

A

2.538

0.906 (0.801 to 1.023)

0.111

0.009

 

R

4.459

0.776 (0.613 to 0.982)

0.035

< 0.001

  1. aThe logistic genetic models were defined as follows:
  2. D, dominant model, defined as 1 (GG + GA) versus 0 (AA);
  3. A, additive model, 2 (GG) versus 1 (GA) versus 0 (AA);
  4. R, recessive model, 1 (GG) versus 0 (GA + AA).
  5. P < 0.05 was considered significant.
  6. ApoE, apolipoprotein E ϵ4; CI: confidence interval; OR: odds ratio; SNP, single-nucleotide polymorphism.
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Journal of Neuroinflammation

ISSN: 1742-2094