Figure 9
From: Involvement of neuronal IL-1β in acquired brain lesions in a rat model of neonatal encephalopathy
Motor behavioral impairments of lipopolysaccharide (LPS) + hypoxia-ischemia (HI)-exposed rats between post-natal day (P)14 and P40. (A) Mean ± standard error of the mean (SEM) travelled distance measured in the open-field test at P15 to P25 in LPS + HI-exposed pups compared to control (Ctl). (B) Mean ± SEM latency to fall of LPS + HI-exposed rats versus Ctl in the rotarod test at P30 to P40. (C) Mean ± SEM score of circling behavior at P14 in LPS + HI-exposed pups versus Ctl (10 to 14 pups per experimental condition). Unpaired t-test with Welch correction; *** P ≤ 0.001. m meter, s second.