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Figure 2 | Journal of Neuroinflammation

Figure 2

From: Inflammatory demyelination induces glia alterations and ganglion cell loss in the retina of an experimental autoimmune encephalomyelitis model

Figure 2

Scores used for evaluation of EAE symptoms. Mice were examined daily using a clinical EAE scoring system ranging from 0 (no signs) to 5 (complete paralysis). The clinical symptoms were scored for 23 days. Symptoms peaked at day 15 (CO: 0 ± 0, EAE: 2.6 ± 0.3, P< 0.0001) and started to decline at day 17 post immunization. The abscissa represents the experimental days and the ordinate represents the severity of clinical symptoms (n = 8 to 9 animals/group). Black=CO, gray=EAE; *: p<0.05; **: p<0.01; ***: p<0.001. CO, control; EAE, experimental autoimmune encephalomyelitis.

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