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Figure 1 | Journal of Neuroinflammation

Figure 1

From: TSG (2,3,4’ ,5-tetrahydroxystilbene 2-O-β-D-glucoside) suppresses induction of pro-inflammatory factors by attenuating the binding activity of nuclear factor-κB in microglia

Figure 1

Effects of TSG on induction of inducible nitric oxide (iNOS) protein in BV-2 cells stimulated with lipolysaccharide (LPS). (A) Representative images showing that TSG pretreatment (30 minutes) inhibited iNOS expression in LPS-stimulated BV-2 cells at different concentrations (1, 10, 30, 50 μM). (B) Quantitative analysis of iNOS expression in cells upon LPS/TSG treatment (*P < 0.05 versus control). (C) Representative images showing the time-dependent effect of TSG on iNOS expression in LPS-stimulated BV-2 cells. (D) A time-course analysis of iNOS expression upon TSG incubation (*P < 0.05, **P < 0.01 versus control). (E) Quantitative analysis of the cell viability after TSG treatment at concentrations ranging from 1 to 50 μM (n = 6). All data were shown as mean ± standard error. Experiments were performed three times independently. NS, no significance; GAPDH, glyceraldehyde-3-phosphate dehydrogenase.

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Journal of Neuroinflammation

ISSN: 1742-2094