Skip to main content

Table 2 Interpretation of model parameters

From: Cerebral inflammation and mobilization of the peripheral immune system following global hypoxia-ischemia in preterm sheep

Group (Sham) Captures IBI length differences in means between SHAM and HI averaged over all time points
Dummy pre-post UCO (pre-time) Captures the (vertical) shift of mean IBI values, induced by the interrupted treatment (UCO)
Group*pre-post dummy Captures the differential shift of mean IBI length values immediately after UCO - significant only for the HI group
Pre-UCO time Captures a linear increase of mean IBI length over time before UCO Note: Non-significant
Post-UCO time All 3 time associated parameters capture curve-linear changes of mean IBI lengths over time after UCO
Post-UCO time (2)
Post-UCO time (3)
Residual variance Captures within subjects variability (noise)
Random intercept variance, pre-UCO time Captures between subject variability at the outset
Random slope variance, pre-UCO time Captures between subject variability with respect to linear IBI changes over time before UCO (each animal has its own slope)
Random slope variance, post-UCO time HI Captures heterogeneity of between subject variability with respect to linear IBI changes over time after UCO; larger variable responsiveness for the HI group