Figure 2
From: Scolopendra subspinipes mutilans attenuates neuroinflammation in symptomatic hSOD1G93Amice
SSM treatment reduces the expression of Iba-1 and GFAP in 113-day-old hSOD1G93Amice. Representative photomicrographs of Iba-1 (A) and GFAP (B) staining in the lumbar spinal cord. Each column on the right depicts a magnified image of the rectangular region of the corresponding image in the left column. (C) Representative Western blot showing the activation of microglia using an Iba-1 antibody and the detection of astrocytes with a GFAP antibody in the brainstems and spinal cords of hSOD1G93A mice. (D) Quantitative analysis of the levels of Iba1/tubulin and GFAP/tubulin, respectively. The data are presented as the means ± SEM (N = 6 animals/genotype). Statistical significance was assessed via t-test. **P < 0.01 compared to the saline-treated group. SSM: Scolopendra subspinipes mutilans, BS: brainstem, SP: spinal cord.