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Figure 1 | Journal of Neuroinflammation

Figure 1

From: Increased expression of T cell immunoglobulin and mucin domain 3 aggravates brain inflammation via regulation of the function of microglia/macrophages after intracerebral hemorrhage in mice

Figure 1

Expression of Tim- 3 positive cells and Tim-3 mRNA in peri-hematomal brain tissues at time-tested points following intracerebral hemorrhage (ICH). A) and B) Immunofluorescence staining showed that the number of Tim-3 positive cells increased at 12 hours in the wild type (WT) ICH group mice (n = 6), with the maximum at Day 1, **P <0.01 versus the WT sham group (mean ± SD). Scale bar = 20 μm. C) Real-time RT-PCR indicated that the expression of Tim-3 mRNA increased at all time-tested points in the ICH group mice (n = 6) and peaked at Day 1. **P <0.01 versus WT sham group (mean ± SD). ‘Relative fold’ meant the level of mRNA of Tim-3 relative to that of beta-actin.

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Journal of Neuroinflammation

ISSN: 1742-2094