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Figure 9 | Journal of Neuroinflammation

Figure 9

From: LPS and TNF alpha modulate AMPA/NMDA receptor subunit expression and induce PGE2 and glutamate release in preterm fetal ovine mixed glial cultures

Figure 9

Pre-OL survival in activated mixed glial cultures exposed after COX-2 and TNF-α inhibition. Immunocytochemistry was used to assess pre-OL survival in mixed glial cultures exposed to TNF-α (A) or LPS (B) alone or in combination with the COX-2 inhibitor, NS398, or TNF-α antibody treatment. Data are presented as mean pre-OL survival as a percentage of total pre-OLs + SEM of four independent experiments. * indicate a significant difference (P <0.05) between treated means compared to time-matched control and # indicate a significant difference (P <0.05) compared to TNF-α or LPS treated means.

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Journal of Neuroinflammation

ISSN: 1742-2094