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Table 2 Baseline inflammatory characteristics

From: Cerebral ischemia initiates an immediate innate immune response in neonates during cardiac surgery

Neutrophils and monocytes

DHCA

ACP

Preoperative

  

 Monocyte count

1.6 (1.3–2.1)

1.9 (1.1–2.1)

  % CD16- monocytes

83 (71–91)

74 (52–83)

  % CD16int monocytes

7.0 (5.0-14)

12 (6.7–22)

  % CD16+ monocytes

7.0 (4.5–15)

10 (5.5–22)

 Neutrophil count

8.2 (5.7–10.6)

6.0 (5.4–8.8)

  Neutrophil CD62L expression

166 (103–257)

294 (221–329)

  Neutrophil CD11b expression

426 (264–717)

523 (265–685)

Start DHCA or ACP

  

 Monocyte count

0.17 (0.09–0.32)

0.20 (0.13–0.27)

  % CD16- monocytes

81 (70–86)

78 (66–85)

  % CD16int monocytes

6.5 (3.5–9.0)

6.6 (3.7–8.6)

  % CD16+ monocytes

14 (7.4–19)

14 (7.3–23)

 Neutrophil count

1.4 (0.8–2.2)

1.0 (0.5–1.4)

  Neutrophil CD62L expression

189 (104–262)

205 (146–288)

  Neutrophil CD11b expression

519 (322–743)

673 (468–792)

Cytokines and chemokines

  

Start DHCA or ACP

  

 IL-1β

0.18 (0.00-1.1)

0.18 (0.00-0.62)

 IL-6

18 (1.0–21)

8.1 (2.3–16)

 IL-8

7.2 (5.6–35)

5.3 (3.0–10)

 IL-10

42 (9.7–61)

12 (6.3–32)

Values corrected for dilution

  

 IL-1β

0.82 (0.72–18)

0.81 (0.78–12)

 IL-6

59 (15–103)

36 (8.1–65)

 IL-8

28 (18–67)

26 (11–65)

 IL-10

105 (42–337)

74 (23–135)

  1. Values represent medians (interquartile ranges). Neutrophil and monocyte counts in 109/L, neutrophil expressions in median fluorescence intensity (MFI), cytokine and chemokine concentrations in pg/ml. ACP, antegrade cerebral perfusion; DHCA, deep hypothermic circulatory arrest.