Figure 2From: Complement activation fragment C5a receptors, CD88 and C5L2, are associated with neurofibrillary pathology C5L2 antibodies label dystrophic neurites associated with plaques as well as neurofibrillary tangles. Representative pictures of C5L2 staining using antibody N1-50 in FC of VD (A) and hippocampus of control (B) and VD (C) brain, and FC (D) or hippocampus of two AD cases (E, F). Arrowhead in D shows dystrophic neurites associated with plaques in cortex (DNP). Insert in E shows DNP in hippocampus. Scale bars: 50 um. AD, Alzheimer’s disease; FC, frontal cortex; VD, vascular dementia.Back to article page