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Table 1 Demographic and clinical characteristics of study participants

From: Plasma cytokine profiling in sibling pairs discordant for autism spectrum disorder

  Children with ASD, n = 25 Healthy siblings, n = 25 Z score P value
Ethnicity, n (%)    
 Caucasian 21 (88.0)
 Hispanic 1 (4.0)
 Caucasian-Hispanic 1 (4.0)
 Asian 1 (4.0)
Age, years, mean ± SD 8.11 ± 3.65 7.44 ± 3.12 1.232 0.218
VABS scores, median ± IQR/2     
 Communication 54.5 ± 14.3 100.0 ± 10.5 −3.945 3.9 × 10 -5
 Daily living skills 55.5 ± 12.8 95.0 ± 11.5 −3.875 5.3 × 10 -5
 Motor skills 75.0 ± 12.5 103.0 ± 8.5 −3.180 7.4 × 10 -4
 Composite 53.5 ± 10.8 94.0 ± 11.0 −3.920 4.4 × 10 -5
SRS scores, mean ± SD     
 Social awareness 75.3 ± 11.0 46.8 ± 10.3 3.516 2.2 × 10 -4
 Social cognition 80.8 ± 11.4 46.2 ± 7.7 3.516 2.2 × 10 -4
 Social communication 82.9 ± 11.7 47.1 ± 13.1 3.516 2.2 × 10 -4
 Social motivation 76.6 ± 10.7 49.8 ± 15.8 3.258 5.6 × 10 -4
 Mannerisms 85.8 ± 12.6 49.1 ± 14.0 3.516 2.2 × 10 -4
 T score, total 85.8 ± 11.8 47.3 ± 12.8 3.516 2.2 × 10 -4
Head circumference, median percentile ± IQR/2 82.0 ± 16.0 84.0 ± 10.0 −0.805 0.421
Full IQ, median ± IQR/2 71.0 ± 12.0 105.5 ± 10.0 −2.201 0.028
Subgroups, n (%)     
 Non-verbal 7 (28.0) NA
 GI issues 7 (28.0) NA
 Regression 8 (32.0) NA
 Allergy history 5 (20.0) NA
  1. Abbreviations: GI, gastrointestinal; IQR/2, semi-interquartile range; NA, not assessed; SD, standard deviation. Significant differences are shown in bold.